How much plaquenil does it take to overdose

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When plaquenil is taken for long periods of time, there is an increased risk to the unborn child.

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All patients on long-term therapy with this preparation should be questioned and examined periodicallyincluding the testing of knee and ankle reflexesto detect any evidence of muscular weaknessIf weakness occursdiscontinue the drug.

Before starting a long-term treatmentboth eyes should be carefully examined for visual acuitycentral visual fieldand color visionExamination should also include fundoscopyThese examinations should be repeated at least annuallyRetinal toxicity is largely dose-related.

If there is any indication of abnormality in the visual acuityvisual fieldcolor visionor retinal macular areassuch as pigmentary changesloss of foveal reflexor any visual symptomssuch as light flashes and streakswhich are not fully explainable by difficulties of accommodation or corneal opacitiesthe drug should be discontinued immediately and the patient closely observed for possible progressionRetinal changesand visual disturbancesmay progress even after cessation of therapysee ADVERSE REACTIONS

Contact your doctor if you experience these side effects and they are severe or bothersomeYour pharmacist may be able to advise you on managing side effects.

Skeletal muscle palsies or skeletal muscle myopathy or neuromyopathy leading to progressive weakness and atrophy of proximal muscle groups which may be associated with mild sensory changesdepression of tendon reflexes and abnormal nerve conduction.

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